Browsing Surgery (Scholarly Publications) by Title
Now showing items 83-102 of 130
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National Standards for Provision and Outcomes in Adult and Paediatric Burn Care
(2018)The ‘National Standards for Provision and Outcomes in Adult and Paediatric Burn Care’ presented here are the result of a collaboration between the British Burn Association (BBA) and the burn care Operational Delivery ... -
Noncoding RNAs in prostate cancer: the long and the short of it.
(2014)As the leading culprit in cancer incidence for American men, prostate cancer continues to pose significant diagnostic, prognostic, and therapeutic tribulations for clinicians. The vast spectrum of disease behavior warrants ... -
Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression.
(American Heart Association, 2003)Background? Pulmonary hypertension induced by chronic hypoxia is characterized by thickening of pulmonary artery walls, elevated pulmonary vascular resistance, and right-heart failure. Prostacyclin analogues reduce pulmonary ... -
Pancreatic anastomosis after pancreatoduodenectomy: A position statement by the International Study Group of Pancreatic Surgery (ISGPS)
(2016)Clinically relevant postoperative pancreatic fistula (grades B and C of the ISGPS definition) remains the most troublesome complication after pancreatoduodenectomy. The approach to management of the pancreatic remnant via ... -
Patent nasopalatine ducts: Evidence to support persistence of the vomeronasal system?
(2018)The vomeronasal system is comprised of the nasopalatine duct and the vomeronasal organ. While this system functions in chemodetection in mammals, its presence and function in adult humans remains to be clearly elucidated. ... -
Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett's Esophagus.
(2015)Barrett ’ s esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within the HLA region) ... -
Postoperative exercise training is associated with reduced respiratory infection rates and early discharge: A case-control study
(2015)Introduction Pulmonary complications are a significant cause of morbidity, mortality and increased hospital stay following complex abdominal surgery. We investigated whether postoperative early aerobic activity with a ... -
Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer
(2016)Colorectal cancer (CRC) is a leading cause of cancer deaths. Molecularly targeted therapies (e.g. bevacizumab) have improved survival rates but drug resistance ultimately develops and newer therapies are required. We ... -
Predicting response to vascular endothelial growth factor inhibitor and chemotherapy in metastatic colorectal cancer.
(2014)Background Bevacizumab improves progression free survival (PFS) and overall survival (OS) in metastatic colorectal cancer patients however currently there are no biomarkers that predict response to this treatment. The ... -
Presentation and management of gastrointestinal stromal tumours.
(2013)Duodenal gastrointestinal stromal tumors (GIST) have been described primarily in isolated case reports. In order to learn more about duodenal GIST, a retrospective review of patients with GIST managed at a single institution ... -
Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue
(2011)Obesity has been associated with increased incidence and mortality of oesophageal and colorectal adenocarcinoma. Excess central adiposity may drive this association through an altered inflammatory milieu. Utilizing a unique ... -
Prognostic significance of neuroepithelial transforming gene 1 in adenocarcinoma of the oesophagogastric junction.
(2014)BACKGROUND: Neuroepithelial transforming gene 1 (NET1) mediates tumour invasion and metastasis in a number of cancers, including gastric adenocarcinoma. It is an indicator of poor prognosis in breast cancer and glioma. ... -
A prospective investigation of predictive and modifiable risk factors for breast cancer in unaffected BRCA1 and BRCA2 gene carriers
(2013)Background Breast cancer is the most common female cancer worldwide. The lifetime risk of a woman being diagnosed with breast cancer is approximately 12.5%. For women who carry the deleterious mutation in either of the ... -
Protein Kinase C Beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival
(2016)Despite extensive efforts, cancer therapies directed at the Protein Kinase C (PKC) family of serine/threonine kinases have failed in clinical trials. These therapies have been directed at inhibiting PKC and have, in some ... -
Radiation and immunotherapy in upper gastrointestinal cancers: The current state of play
(2021)Radiotherapy remains one of the contemporary cornerstones of cancer treatment in the neoadjuvant, curative, adjuvant and palliative settings, either in isolation or as a multimodal approach. Moreover, recent advances in ...