Browsing Biochemistry (Scholarly Publications) by Author "ARMSTRONG, MICHELLE"
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Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent
MILLS, KINGSTON; LAVELLE, EDWARD; ARMSTRONG, MICHELLE (2004)Adenylate cyclase toxin (CyaA) from Bordetella pertussis can subvert host immune responses allowing bacterial colonization. Here we have examined its adjuvant and immunomodulatory properties and the possible contribution ... -
Proinflammatory Responses in the Murine Brain after Intranasal Delivery of Cholera Toxin: Implications for the Use of AB Toxins as Adjuvants in Intranasal Vaccines
LAVELLE, EDWARD; MILLS, KINGSTON; LYNCH, MARINA; ARMSTRONG, MICHELLE (2005)Intranasal delivery of vaccines provides an attractive alternative to parenteral delivery, but it requires appropriate mucosal adjuvants. Cholera toxin (CT) is a powerful mucosal adjuvant, but it can undergo retrograde ...