Chemistry
Collections in this Academic/Research Unit
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Chemistry (Live Theses)
Chemistry (Live Theses) -
Chemistry (Scholarly Publications)
Chemistry (Scholarly Publications) -
Chemistry (Theses and Dissertations)
Chemistry (Theses and Dissertations)
Recent Submissions
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Wedge disclination description of emergent core-shifted grain boundaries at free surfaces
(2023)Emergent grain boundaries at free surface control material properties such as nanomaterial strength, catalysis, and corrosion. Recently the restructuring of emergent boundaries on copper (111) surfaces was discovered ... -
Micro and nano plastics release from a single absorbable suture into simulated body fluid
(2024)Synthetic polymers are widely used in medical devices and implants where biocompatibility and mechanical strength are key enablers of emerging technologies. One concern that has not been widely studied is the potential of ... -
Liquid Phase Exfoliation, characterization, and printing of SnSe and PtSe2 devices
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The demand for optical-to-electrical and/or electrical-to-optical transducers is growing exponentially as optics are increasingly adopted for energy-efficient data transmission. Displays and light sensors are increasingly ... -
Core shift controls grain boundary energy scaling in Cu and Al
(2024)Grain boundary energies in different elements are correlated. The proportional scaling constants relating the energies of crystallography-equivalent boundaries in any two f.c.c. elements are nearly constant, with the ... -
Characterisation of Structure-Property Relationships in Novel Chalcogenides Systems
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)As devices become smaller and head towards the atomic limits, minute changes in their structure, in the form of defects, can have an oversized effect on the device properties. This is especially true for novel classes of ... -
High levels of microparticles release from biodegradable polylactic acid paper cups compared with polyethylene-lined cups
(2023)Polylactic acid (PLA) is a popular replacement for conventional fossil-fuel based plastics products such as polyethylene (PE) due to its high biodegradability and recyclability. Previous studies confirmed that PLA microplastics ... -
Exploring the Diverse Landscape of Layered Double Hydroxide-Based Nanomaterials
(Trinity College Dublin. School of Chemistry. Discipline of ChemistryTrinity College Dublin, School of Chemistry, 2024)This thesis details the synthesis, characterisation, and an exploration of the diverse application landscape of layered double hydroxide (LDH)-based nanomaterials. The aim is to showcase the potential of LDHs in chirality ... -
Nucleoside and Oligonucleotide Modification for Targeting the DNA Damage Repair Enzyme SNM1A
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The exonuclease SNM1A is a key enzyme involved in the repair of interstrand crosslinks, a highly cytotoxic form of DNA damage. As cells depleted in this enzyme display increased sensitivity to chemotherapeutic agents such ... -
Exploring new techniques for the surface modification of high-performance polymer materials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The surface modification of high-performance polymers is a critical area of research, as these materials possess excellent mechanical, chemical, and thermal properties but often lack the surface functionality required for ... -
Novel Chemical Modalities and Methods for Protein Profiling
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)The activity of proteins is pivotal to the chemistry of cells. In order to deconvolute the complexity of living systems, chemical tools can be used to study active proteins under different cellular states. Amongst these ... -
Tailored nitrogen-containing polyaromatics - from surfaces to stacks
(Trinity College (Dublin, Ireland). School of Chemistry, 2016)Chapter 1: This chapter gives a broad introduction to the subjects of graphene and nanographenes, which are discussed in subsequent chapters. Common methodologies for the synthesis of substituted polyphenylenes and ... -
Development of a solution-based process for hydroxyapatite and functionalised hydroxyapatite
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Hydroxyapatite coatings have long been established as a means of improving the osteointegration of metallic orthopaedic implants. Nonetheless there are both technical and commercial drawbacks associated with industrial ... -
Development of Stimuli-responsive Materials for Direct Laser Writing for the Realisation of Microactuators
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Two-photon polymerisation (2PP) is a laser-based fabrication technology which can be used to fabricate complex 3D microstructures with feature sizes ~100 nm. This thesis assesses the state of the art in 2PP and presents ... -
Enantioselective effect of cysteine functionalized mesoporous silica nanoparticles in U87 MG and GM08680 human cells and Staphylococcus aureus bacteria
(2021)Chirality is a fundamental phenomenon in biological systems, since most of the biomolecules and biological components and species are chiral and therefore recognize and respond differently depending on the enantiomer ... -
On-Surface Synthesis of Polyphenylene Wires Comprising Rigid Aliphatic Bicyclo[1.1.1]Pentane Isolator Units
(2023)Bicyclo[1.1.1]pentane (BCP) motifs are of growing importance to the pharmaceutical industry as sp3 -rich bioisosteres of benzene rings and as molecular building blocks in materials science. Herein we explore the behavior ... -
A Heterometallic Porphyrin Dimer as a Potential Quantum Gate: Magneto-Structural Correlations and Spin Coherence Properties
(2023)In the development of two-qubit quantum gates, precise control over the intramolecular spin-spin interaction between molecular spin units plays a pivotal role. A weak but measurable exchange coupling is especially important ... -
Supramolecular Chirogenesis in a Sterically Hindered Porphyrin: A Critical Theoretical Analysis
(2023)Invited for the cover of this issue are the groups of Irina Osadchuk at Tallinn University of Technology and Mathias Senge at Trinity College Dublin. The image depicts how a porphyrin with two guest molecules (R)-camphor ... -
Structure of (R,R)-4-bromo-2-{4-[4-bromo-1-(4-toluenesulfonyl)-1H-pyrrol-2-yl]-1,3-dinitrobutan-2-yl}-1-(4-toluenesulfonyl)-1H-pyrrole, another ostensible by-product in the synthesis of geminal-dimethyl hydrodipyrrins
(2023)The crystal structure of (R,R)-4-bromo-2-{4-[4-bromo-1-(4-toluenesulfonyl)-1H-pyrrol-2-yl]-1,3-dinitrobutan-2-yl}-1-(4-toluenesulfonyl)-1H-pyrrole (1, C26H24Br2N4O8S2) is presented. The title compound was isolated ... -
Strapped Porphyrins as Model Systems for Atropisomeric Photosensitizer Drugs
(2023)The time dependence of atropisomer interconversion has limited the pursuit of single atropisomer drug candidates, even in circumstances where one atropisomer presents favorable biological activity over another. Moderate ... -
The Photosensitizer Temoporfin (mTHPC) - Chemical, Pre-clinical and Clinical Developments in the Last Decade
(2023)This review follows the research, development and clinical applications of the photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (mTHPC, temoporfin) in photodynamic (cancer) therapy (PDT) and other medical applications. ...