Browsing Clinical Medicine by Title
Now showing items 377-396 of 949
-
Habitual physical activity and cardiometabolic risk factors in adults with cerebral palsy
(2014)Adults with cerebral palsy (CP) are known to participate in reduced levels of total physical activity. There is no information available however, regarding levels of moderate-to-vigorous physical activity (MVPA) in this ... -
Halloysite- and Montmorillonite-Loaded Scaffolds as Enhancers of Chronic Wound Healing
(2020)The increase in life expectancy and the increasing prevalence of diabetic disease and venous insufficiency lead to the increase of chronic wounds. The prevalence of ulcers ranges from 1% in the adult population to 3–5% in ... -
Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma.
(2012)Palmoplantar keratodermas (PPKs) are a group of disorders that are diagnostically and therapeutically problematic in dermatogenetics. Punctate PPKs are characterized by circumscribed hyperkeratotic lesions on the palms and ... -
Harmonic and superparamagnetic nanoparticles for biomedical imaging and diagnostic applications
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)Diagnosing certain diseases and tracking their progression requires the ability to 'see' into the body. This is typically achieved by taking advantage of intrinsic contrast in biological tissues (such as in X-ray or magnetic ... -
Healthy Eating, Food Safety and Food Legislation: A Guide Supporting the Healthy Ireland Food Pyramid
(2019)This guide provides extended information to support the Healthy Ireland Food Pyramid 2016, which is based on international best practice and tailored to meet the specific needs of Ireland’s population. These healthy ... -
Heart Rate Recovery Velocity in Cardiac Disease
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Introduction Rate of recovery of heart rate between 10 and 20 seconds following orthostatic challenge (HRR10-20) is a risk factor for all-cause mortality. Furthermore, both cardiac rehabilitation and completeness of coronary ... -
Helminth infection protects mice from anaphylaxis via IL-10 producing B cells
(The American Association of Immunologists, 2004)Modulation of the immune system by infection with helminth parasites, including schistosomes, is proposed to reduce the levels of allergic responses in infected individuals. In this study we investigated whether experimental ... -
Helminth therapies: translating the unknown unknowns to known knowns.
(2013)The use of live helminth infections is currently in clinical trials as a novel approach for the treatment of a range of allergic and autoimmune diseases. This rapid progression from observational studies some 20 years ago ... -
Helminth-modified pulmonary response protects mice from allergen-induced airway hyper-responsiveness.
(The American Association of Immunologists, 2006)It has been shown that the presence of certain helminth infections in humans, including schistosomes, may reduce the propensity to develop allergies in infected populations. Using a mouse model of schistosome worm vs worm ... -
Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion.
(2011)T cell activation and the resultant production of interleukin (IL-2) is a central response of the adaptive immune system to pathogens, such as hepatitis C virus (HCV). HCV uses sev- eral mechanisms to evade both the ... -
Herpes zoster in the T1 dermatome presenting with Horner?s syndrome, radicular weakness, and postherpetic neuralgia
(Dove Medical Press, 2008)Herpes zoster is caused by varicella zoster virus infection involving the dorsal root ganglia of spinal nerve roots. This common problem can be associated with multiple neurological abnormalities. We present a case of ... -
High content analysis of cellular localisation and biocompatibility of CdTe and CdSe / ZnS nanoparticles
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2010)The rules governing particle properties at the nanoscale relate more to the laws of quantum mechanics than classical mechanics. Biologists have been keen to harness nanoparticles not only for these properties but also ... -
High Prevalence of Antibiotic Resistance in Iranian Helicobacter pylori Isolates: Importance of Functional and Mutational Analysis of Resistance Genes and Virulence Genotyping
(2019)The high prevalence of antibiotic resistance in Helicobacter pylori has become a great challenge in Iran. The genetic mutations that contribute to the resistance have yet to be precisely identified. This study aimed to ... -
High prevalence of dementia among community dwelling older adults in receipt of state funded home care packages: implications for health care planning
(2017)Objectives: The majority of people living with dementia in Ireland reside in their own homes, some supported by formal or informal home care. This audit aimed to estimate the prevalence of dementia and suspected cognitive ... -
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.
(2013)Atopic dermatitis is a common inflammatory skin disease with a strong heritable component. Pathogenetic models consider keratinocyte differentiation defects and immune alterations as scaffolds, and recent data indicate a ... -
HIP FRACTURES IN OLDER ADULTS AND TREATMENT WITH INTRAVENOUS ZOLEDRONIC ACID
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Introduction: Osteoporotic hip fractures are common in older adults and are responsible for significant morbidity and mortality. Structured geriatric care for older adults with hip fracture is known to improve outcomes. A ...