Browsing by Author "CONNON, STEPHEN"
Now showing items 21-29 of 29
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NHC-Catalysed, chemoselective crossed-acyloin reactions
GUNDALA , SIVAJI; CONNON, STEPHEN (2012)It has been shown for the first time that relatively electron deficient triazolium pre-catalysts promote (at low loadings in the presence of base) highly chemoselective crossed acyloin condensation reactions between aldehydes ... -
Novel amine-catalysed hydroalkoxylation reactions of alkenes and alkynes
CONNON, STEPHEN (2005)Substoichiometric loadings of DBU catalyse the efficient 1,4- addition of alcohols and non-nucleophilic amines such as pyrrole to activated alkenes; the application of this methodology in a one-pot synthesis of a natural ... -
A reductase-mimicking thiourea organocatalyst incorporating a covalently bound NADH analogue: Efficient 1,2-diketone reduction with in situ prosthetic group generation and recycling
CONNON, STEPHEN (Royal Society of Chemistry, 2007)A new class of bifunctional organocatalyst promotes the chemoselective reduction of diketone electrophiles at catalytic loadings in the presence of an inorganic co-reductant. -
Substituted 3,4-pyridynes: clean cycloadditions
CONNON, STEPHEN (Royal Society of Chemistry, 2000)The stabilisation of 3,4-pyridyne (1) by an alkoxy group adjacent to the ring nitrogen is reported. The regioselective lithiation of 2-ethoxy- (14), 2-methoxy- (18), 2-isopropoxy- (19) and 6-isopropoxy- (26) -3-chloropyridines ... -
Synergistic organocatalysis in the kinetic resolution of secondary thiols with concomitant desymmetrisation of an anhydride.
CONNON, STEPHEN; PROCURANTI, BARBARA; PESCHIULLI, ALDO (2010)An organocatalytic process mediated by a single small-molecule catalyst involving the highly enantioselective desymmetrisation of an achiral electrophile while it simultaneously kinetically resolves a racemic nucleophile ... -
Tandem ionic liquid antimicrobial toxicity and asymmetric catalysis study: carbonyl-ene reactions with trifluoropyruvate
CONNON, STEPHEN (2013)Imidazolium Brønsted acidic catalysts substituted with ester/amides have been assessed for both antimicrobial toxicity and biodegradation. Low toxicity to a screen of 20 microbial strains (12 fungi and 8 bacteria) was ... -
Tunable bromomagnesium thiolate Tishchenko reaction catalysts: efficient intermolecular aldehyde-trifluoromethylketone coupling
CONNON, STEPHEN (2010)A new thiolate-catalyzed Tishchenko reaction inspired by biochemical processes features exceptionally good control over the catalyst's steric/electronic properties. The isolation of reaction intermediates provided valuable ... -
Urea derivatives are highly active catalysts for the base-mediated generation of terminal epoxides from aldehydes and trimethylsulfonium iodide
CONNON, STEPHEN; PICCININI, ALESSANDRO (2008)N,N?-Diarylureas have been shown to efficiently catalyse sulfonium ylide-mediated aldehyde epoxidation reactions for the first time. These processes are of broad scope and can be coupled with a subsequent Cu(II) ion-catalysed ...