Browsing by Author "REYNOLDS, JOHN"
Now showing items 21-38 of 38
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Management of gastro-bronchial fistula complicating a subtotal esophagectomy: a case report
REYNOLDS, JOHN; RAVI, NARAYANASAMY (BioMed Central, 2009)Background The development of a fistula between the tracheobronchial tree and the gastric conduit post esophagectomy is a rare and often fatal complication. Case presentation A 68 year old man underwent radical ... -
Management of maple syrup urine disease in the peri-operative period.
REYNOLDS, JOHN; RAVI, NARAYANASAMY (2013) -
Management of synchronous adenocarcinoma of the esophago-gastric junction and ampulla of Vater: case report of a surgically challenging condition
REYNOLDS, JOHN (BioMed Central, 2009)We report herein a case of a synchronous presentation of an adenocarcinoma of esophagago-gastric junction type II and an ampullary tumor that was treated by combined Whipple's pancreaticoduodenectomy, total gastrectomy and ... -
MicroRNA-330-5p as a putative modulator of neoadjuvant chemoradiotherapy sensitivity in oesophageal adenocarcinoma
REYNOLDS, JOHN; MAHER, STEPHEN (2015)Oesophageal adenocarcinoma (OAC) is the sixth most common cause of cancer deaths worldwide, and the 5-year survival rate for patients diagnosed with the disease is approximately 17%. The standard of care for locally advanced ... -
Modern operative and oncological outcome in oesophagel cancer
REYNOLDS, JOHN; DONOHOE, CLAIRE; HOLLYWOOD, DONAL; O'BYRNE, KEN; RAVI, NARAYANASAMY (2011) -
Nanodrug applications in photodynamic therapy.
EHRHARDT, CARSTEN; SENGE, MATHIAS; KELLEHER, DERMOT P; REYNOLDS, JOHN (2011) -
Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (the PREPARE study): study protocol for a randomized controlled trial
GUINAN, EMER; REYNOLDS, JOHN (2014)BACKGROUND: Esophageal resection is associated with a high incidence of postoperative pneumonia. Respiratory complications account for almost half of the readmissions to the critical care unit. Postoperative complications ... -
Presentation and management of gastrointestinal stromal tumours.
REYNOLDS, JOHN; MULDOON, CIAN; RAVI, NARAYANASAMY (2013)Duodenal gastrointestinal stromal tumors (GIST) have been described primarily in isolated case reports. In order to learn more about duodenal GIST, a retrospective review of patients with GIST managed at a single institution ... -
Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue
ALLOTT, EMMA; PIDGEON, GRAHAM; LYSAGHT, JOANNE; REYNOLDS, JOHN; DONOHOE, CLAIRE; HOWARD, JULIA MARY; RAVI, NARAYANASAMY; CASEY, RORY (2011)Obesity has been associated with increased incidence and mortality of oesophageal and colorectal adenocarcinoma. Excess central adiposity may drive this association through an altered inflammatory milieu. Utilizing a unique ... -
Prognostic significance of neuroepithelial transforming gene 1 in adenocarcinoma of the oesophagogastric junction.
CATHCART, MARY; PIDGEON, GRAHAM; REYNOLDS, JOHN; MULDOON, CIAN (2014)BACKGROUND: Neuroepithelial transforming gene 1 (NET1) mediates tumour invasion and metastasis in a number of cancers, including gastric adenocarcinoma. It is an indicator of poor prognosis in breast cancer and glioma. ... -
The role of obesity in gastrointestinal cancer: evidence and opinion
REYNOLDS, JOHN; DOYLE, SUZANNE (2014) -
The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer
PIDGEON, GRAHAM; REYNOLDS, JOHN; O'BYRNE, KEN (2010)Prostacyclin synthase and thromboxane synthase signaling via arachidonic acid metabolism affects a number of tumor cell survival pathways such as cell proliferation, apoptosis, tumor cell invasion and metastasis, and ... -
Severe epigastric pain following a birthday party.
REYNOLDS, JOHN; RAVI, NARAYANASAMY (2013)Epigastric pain is a very common symptom which can be caused by a wide range of clinical conditions. A 28 year old male presented to our clinic with new onset severe epigastric pain. As part of the routine work up for pain ... -
An unusual presentation of Boerhaave Syndrome: a case report
REYNOLDS, JOHN; RAVI, NARAYANASAMY (BioMed Central, 2009)We present a unique case of Boerhaave Syndrome that may highlight the spectrum of barotrauma from a Mallory-Weiss tear to full-thickness perforation. In this case, perforation only became evident following air insufflation ... -
The value of double balloon enteroscopy in diagnosing blue rubber bleb naevus syndrome: a case report.
RAVI, NARAYANASAMY; REYNOLDS, JOHN (BioMed Central, 2010)Blue rubber bleb naevus syndrome is a rare vascular disorder associated with multiple gastrointestinal haemangiomas that have the potential for life-threatening haemorrhage. These may be difficult to diagnose, and have ... -
Visceral adiposity, insulin resistance and cancer risk
REYNOLDS, JOHN; DONOHOE, CLAIRE (2011)Background: There is a well established link between obesity and cancer. Emerging research is characterising this relationship further and delineating the specific role of excess visceral adiposity, as opposed to simple ...