Browsing by Author "BUCKLEY, CONOR TIMOTHY"
Now showing items 1-4 of 4
-
Dynamic compression can inhibit chondrogenesis of mesenchymal stem cells.
VINARDELL, TATIANA; KELLY, DANIEL; CAMPBELL, VERONICA ANN; BUCKLEY, CONOR TIMOTHY (2008)The objective of this study was to investigate the influence of dynamic compressive loading on chondrogenesis of mesenchymal stem cells (MSCs) in the presence of TGF-?3. Isolated porcine MSCs were suspended in 2% agarose ... -
European Society of Biomechanics S.M. Perren Award 2012: The external mechanical environment can override the influence of local substrate in determining stem cell fate.
KELLY, DANIEL JOHN; THORPE, STEPHEN; STEWARD, ANDREW; BUCKLEY, CONOR TIMOTHY (2012)The aim of this study was to explore how cell-matrix interactions and extrinsic mechanical signals interact to determine stem cell fate in response to transforming growth factor-?3 (TGF-?3). Bone marrow derived mesenchymal ... -
High abundance of CD271+ multipotential stromal cells (MSCs) in intramedullary cavities of long-bones
BUCKLEY, CONOR TIMOTHY (2012)Aspiration of iliac crest bone marrow (ICBM) remains the most frequent technique used in harvesting multipotential stromal cells (MSCs) for bone regeneration. Although this tissue type is easily accessed by a surgeon, it ... -
The role of environmental factors in regulating the development of cartilaginous grafts engineered using osteoarthritic human infrapatellar fat pad-derived stem cells.
KELLY, DANIEL JOHN; BUCKLEY, CONOR TIMOTHY (2012)Engineering functional cartilaginous grafts using stem cells isolated from osteoarthritic human tissue is of fundamental importance if autologous tissue engineering strategies are to be used in the treatment of diseased ...