Browsing by Author "Brint, Elizabeth"

Now showing items 1-2 of 2

    • Characterisation of signalling pathways activated by the IL-1 receptor homologue T1/ST2 

      Brint, Elizabeth (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2003)
      T1/ST2 is a member of the IL-1 receptor family possessing the three characteristic extracellular Ig domains and an intracellular Toll-IL1R (TIR) domain. It is an orphan receptor expressed on a variety of cell types including ...

    • IL-1 family members in health and disease 

      Doyle, Sarah L.; Brint, Elizabeth; Kamradt, Thomas (2019)
      In 1985, two distinct cDNAs encoding proteins sharing human Interleukin-1 (IL-1) activity were described, thus defining the first two members of the IL-1 family – IL-1α and IL-1β. These potent pro-inflammatory cytokines ...