Browsing by Author "Gobbo, Oliviero"

Now showing items 1-6 of 6

    • Assessment of renal function in the anaesthetised rat following injection of superparamagnetic iron oxide nanoparticles 

      Gobbo, Oliviero; Edge, Deirdre; Shortt, Christine M.; Johns, E.J.; Markos, Farouk; Abdulla, Mohammed H.; Barry, Elaine F. (2017)
      A recent study showed that a significant fall in mean arterial pressure (MAP) occurred following intravenous injection of two novel superparamagnetic iron oxide nanoparticles (SPIONs), MF66 and OD15. To assess if this was ...

    • Biocompatible copolymer formulations to treat glioblastoma multiforme. 

      Gobbo, Oliviero (2021)
      The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years while the prognosis for the patients is still poor and most of them survive less than 1 year after diagnosis. The standard of care for ...

    • An experimental platform for systemic drug delivery to the retina 

      Humphries, Marian; Campbell, Matthew; Gobbo, Oliviero; Farrar, Gwyneth; Humphries, Peter; Kerskens, Christian (2009)
      Degenerative retinopathies, including age-related macular degeneration, diabetic retinopathy, and hereditary retinal disorders?major causes of world blindness?are potentially treatable by using low-molecular weight ...

    • Manganese: a new contrast agent for lung imaging? 

      Ehrhardt, Carsten; Gobbo, Oliviero; Zurek, Magdalena; Tewes, Frederic; Crémillieux, Yannick (2012)
      Lung parenchyma remains one of the most difficult tissues to be imaged by means of magnetic resonance imaging (MRI). Several MRI techniques are routinely used for lung imaging. However, manganese-enhancement MRI ...

    • Recommendations for In Vitro and In Vivo Testing of Magnetic Nanoparticle Hyperthermia Combined with Radiation Therapy. 

      Gobbo, Oliviero; Spirou, Spiridon V.; Costa Lima, Sofia A.; Bouziotis, Penelope; Vranješ-Djurić, Sanja; Efthimiadou, Eleni; Laurenzana, Anna; Barbosa, Ana Isabel; Garcia-Alonso, Ignacio; Jones, Carlton; Jankovic, Drina (2018)
      Magnetic nanoparticle (MNP)-mediated hyperthermia (MH) coupled with radiation therapy (RT) is a novel approach that has the potential to overcome various practical difficulties encountered in cancer treatment. In this work, ...

    • Systemic low-molecular weight drug delivery to pre-selected neuronal regions 

      Humphries, Marian; Kenna, Paul; Campbell, Matthew; Farrar, Gwyneth; Humphries, Peter; Gobbo, Oliviero (2011)
      We describe a procedure for controlled, periodic, reversible modulation of selected regions of the blood-brain barrier (BBB) or the inner-blood-retina barrier (iBRB) based on incorporation into an AAV-2/9 vector of a ...