Browsing by Author "MCDONNELL, CIARA MARY"
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Manipulation of enzyme activity via substrate based control: a new paradigm in drug design
MCDONNELL, CIARA MARY (Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)This thesis documents our approach to the manipulation of enzyme activity in previously underexploited pathways through the design of artificial substrates. It was envisaged that this strategy would enable the discovery ...