Browsing by Author "MILLINGTON-WARD, SOPHIA"
Now showing items 1-3 of 3
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Mitochondrial disorders: aetiologies, models systems, and candidate therapies
MILLINGTON-WARD, SOPHIA; CHADDERTON, NAOMI SARAH; FARRAR, GWYNETH JANE; KENNA, PAUL (2013)It has become evident that many human disorders are characterised by mitochondrial dysfunction either at a primary level, due to mutations in genes whose encoded products are involved in oxidative phosphorylation, or at a ... -
A mutation-independent therapeutic strategy for dominant dystrophic epidermolysis bullosa.
MILLINGTON-WARD, SOPHIA; FARRAR, JANE (2013) -
Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa
MILLINGTON-WARD, SOPHIA; O'REILLY, MARY; PALFI, ARPAD; KILTY, CLAIRE; HUMPHRIES, MARIAN; KENNA, PAUL; FARRAR, JANE; HUMPHRIES, PETER; CHADDERTON, NAOMI (2011)For dominantly inherited disorders development of gene therapies, targeting the primary genetic lesion has been impeded by mutational heterogeneity. An example is rhodopsin-linked autosomal dominant retinitis pigmentosa ...