Browsing by Author "Newman, Louise"
Now showing items 1-10 of 10
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Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA)
Knight, Silvin; Kenny, Rose; Mc Morrow, Jason; Newman, Louise; Meaney, James; Williamson, Wilby (2021)Objective: To establish normative reference values for total grey matter cerebral blood flow (CBFGM) measured using pseudo-continuous arterial spin labelling (pCASL) MRI in a large cohort of community-dwelling adults aged ... -
Associations between Cardiovascular Signal Entropy and Cognitive Performance over Eight Years
Romero-Ortuno, Roman; Knight, Silvin; Kenny, Rose; Newman, Louise (2021)In this study, the relationship between non-invasively measured cardiovascular signal entropy and global cognitive performance was explored in a sample of community-dwelling older adults from The Irish Longitudinal Study ... -
Associations between neurocardiovascular signal entropy and physical frailty
Romero-Ortuno, Roman; Knight, Silvin; Kenny, Rose; Newman, Louise (2021)In this cross-sectional study, the relationship between noninvasively measured neurocardiovascular signal entropy and physical frailty was explored in a sample of community-dwelling older adults from The Irish Longitudinal ... -
Cardiovascular signal entropy predicts all-cause mortality: evidence from The Irish Longitudinal Study on Ageing (TILDA)
Romero-Ortuno, Roman; Knight, Silvin; Ward, Mark; Newman, Louise; Kenny, Rose (2022)In this study, the relationship between cardiovascular signal entropy and the risk of seven-year all-cause mortality was explored in a large sample of community-dwelling older adults from The Irish Longitudinal Study on ... -
Clinical clustering of eight orthostatic haemodynamic patterns in The Irish Longitudinal Study on Ageing (TILDA)
Romero-Ortuno, Roman; Kenny, Rose; Hernández, Belinda; Newman, Louise (2020)Background: Orthostatic hypotension (OH) can be assessed with non-invasive continuous beat-to-beat haemodynamic monitoring during active stand (AS) testing; this yields large volumes of data outside the scope ... -
Eight orthostatic haemodynamic patterns in The Irish Longitudinal Study on Ageing (TILDA): stability and clinical associations after 4 years
Romero-Ortuno, Roman; Kenny, Rose; Newman, Louise; Knight, Silvin (2021)Previous research cross-sectionally characterised eight morphological systolic blood pres-sure (SBP) active stand (AS) patterns using a clinical clustering approach at Wave 1 (W1) of the IrishLongitudinal Study on Ageing. ... -
Functional Analysis of Continuous, High-Resolution Measures in Ageing Research: A Demonstration using Cerebral Oxygenation Data from The Irish Longitudinal Study on Ageing
Knight, Silvin; Hernández, Belinda; Newman, Louise (2020)Background: A shift towards the dynamic measurement of physiologic resilience and improved technology incorporated into experimental paradigms in aging research is producing high-resolution data. Identifying ... -
Hemodynamic and structural brain measures in high and low sedentary older adults
Scarlett, Siobhan; Knight, Silvin; Kenny, Rose; Newman, Louise; Feeney, Joanne (2021)Due to its cardiovascular effects sedentary behaviour might impact cerebrovascular function in the long term, affecting cerebrovascular regulatory mechanisms and perfusion levels. Consequently this could underly potential ... -
Longitudinal study on Sustained Attention to Response Task (SART): clustering approach for mobility and cognitive decline
Romero-Ortuno, Roman; Knight, Silvin; Newman, Louise; Kenny, Rose (2022)The Sustained Attention to Response Task (SART) is a computer-based go/no-go task to measure neurocognitive function in older adults. However, simplified average features of this complex dataset lead to loss of primary ... -
SART and individual trial mistake thresholds: predictive model for mobility decline
Romero-Ortuno, Roman; Knight, Silvin; Kenny, Rose; Newman, Louise (2021)The Sustained Attention to Response Task (SART) has been used to measure neurocognitive functions in older adults. However, simplified average features of this complex dataset may result in loss of primary information and ...