Browsing by Author "O'Sullivan, Shane"
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Nitrate-barbiburate compounds inhibit matrix metalloproteinase-9 in in-vitro and in-vivo models of intestinal inflammation
O'Sullivan, Shane (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2014)Inflammatory bowel disease is characterised by a dysregulated immune response and a compromised epithelial barrier. The enzyme matrix metalloproteinase-9 (MMP-9) is upregulated in an inflammatory setting and is believed ...