Browsing by Author "Pidgeon, Graham"
Now showing items 1-7 of 7
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Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
Pidgeon, Graham; Lysaght, Joanne; O'Byrne, Ken; Gately, Kathy (2016)Background Baicalein is a widely used Chinese herbal medicine derived from Scutellaria baicalenesis, which has been traditionally used as anti-inflammatory and anti-cancer therapy. In this study we examined the anti-tumour ... -
Excess visceral adiposity induces alterations in mitochondrial function and energy metabolism in esophageal adenocarcinoma.
Lysaght, Joanne; Pidgeon, Graham; Lynam-Lennon, Niamh (2014)Background: Visceral obesity has a strong association with both the incidence and mortality of esophageal adenocarcinoma (EAC). Alterations in mitochondrial function and energy metabolism is an emerging hallmark of cancer, ... -
Excess visceral adiposity induces alterations in mitochondrial function and energy metabolism in esophageal adenocarcinoma.
O'Sullivan, Jacintha; Pidgeon, Graham; Reynolds, John; Porter, Richard; Lynam-Lennon, Niamh (2014)Background Visceral obesity has a strong association with both the incidence and mortality of esophageal adenocarcinoma (EAC). Alterations in mitochondrial function and energy metabolism is an emerging hallmark of cancer, ... -
Innovative technologies changing cancer treatment
Pidgeon, Graham (2018) -
Leptin and adiponectin receptor expression in oesophageal cancer.
Pidgeon, Graham; Reynolds, John; Beddy, Peter (2014)BACKGROUND: Oesophageal adenocarcinoma is an exemplar model of an obesity-associated adenocarcinoma. Altered secretion of adipokines by visceral fat is believed to play a key role in tumorigenesis. This study examined ... -
Prevalence of age-related macular degeneration in the Republic of Ireland.
Kenny, Rose; O'Halloran, Aisling; Pidgeon, Graham; Feeney, Joanne (2015)Background Age-related macular degeneration (AMD) remains the most common cause of visual loss among subjects over 50 years of age in the developed world. The Irish Longitudinal study on Ageing (TILDA) is a population-based ... -
Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma.
Lynam-Lennon, Niamh; Pidgeon, Graham; Lysaght, Joanne; Reynolds, John (2019)Oesophageal adenocarcinoma (OAC) is an exemplar model of obesity-associated cancer. Response to neoadjuvant chemoradiotherapy (NA CRT) is a clinical challenge. We examined if visceral adipose tissue and obesity ...