Browsing by Author "Sommerville, Gary"
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MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype
Maher, Stephen; Lynam-Lennon, Niamh; Reynolds, John; O'Leary, John; Heavey, Susan; Sommerville, Gary; Bibby, Becky A.S.; Ffrench, Brendan; Quinn, Jennifer; Gasch, Claudia; Gallagher, Michael F. (2017)Resistance to neoadjuvant chemoradiation therapy (CRT) remains a critical barrier to the effective treatment of esophageal adenocarcinoma (EAC). Cancer stem-like cells (CSCs) are a distinct subpopulation of cells implicated ... -
Non-coding RNA expression in cancer stem cell progenies derived from tumours +/-BRAF V600E mutation
Sommerville, Gary (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2013)Cancer has placed a huge burden on the global health system and rising rates in particular cancer types such as lung cancer and melanoma due to smoking and increased UV ray exposure respectively has highlighted the need ...