Browsing by Author "ZISTERER, DANIELA"
Now showing items 1-4 of 4
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Induction of apoptosis in oral squamous carcinoma cells by pyrrolo-1,5-benzoxazepines.
WILLIAMS, DAVID; ZISTERER, DANIELA; O'SULLIVAN, JEFFREY; O'Callaghan, Kate; Palagano, Eleonora; Butini, Stefania; Campiani, Giuseppe (2015)Oral cancer (OC) is a largely asymptomatic disease, resulting in one of the highest mortality rates of any cancer. OC is currently ranked as the sixth most common cancer in the world, according to a recent World Health ... -
Novel Microtubule targetting agents, pyrrolo-1,5,benzoxazepines induce apoptosis in multi-drug-resistant cancer cells
LLOYD, DAVID; ZISTERER, DANIELA; WILLIAMS, DAVID; FAYNE, DARREN (2010)PURPOSE: The development of multi-drug resistance (MDR) due to the expression of members of the ATPase binding cassette (ABC) transporter family is a major obstacle in cancer treatment. The broad range of substrate ... -
Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents
LLOYD, DAVID; NATHWANI, SEEMA; MCCABE, THOMAS; MEEGAN, MARY; GREENE, LISA; O'BOYLE, NIAMH; ZISTERER, DANIELA (2010) -
Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
MEEGAN, MARY; GREENE, LISA; O'BOYLE, NIAMH; MCCABE, THOMAS; ZISTERER, DANIELA; LLOYD, DAVID (2011)A series of azetidin-2-ones substituted at positions 2, 3 and 4 of the azetidinone ring scaffold were synthesised and evaluated for antiproliferative, cytotoxic and tubulin binding activity. In these compounds, the cis ...