Browsing by Subject "Autoimmune disease"
Now showing items 1-4 of 4
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The microbiota and immune-mediated diseases: Opportunities for therapeutic intervention
(2020)A multitude of diverse microorganisms, termed the microbiota, reside in the gut, respiratory tract, skin, and genital tract of humans and other animals. Recent advances in metagenomic sequencing and bioinformatics have ... -
Modulation of immune responses by Fasciola hepatica-derived products
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2019)Helminths are successful pathogens that infect 25% of the world s population. They cause chronic infections that are associated with type-2 and regulatory immune responses that suppress host anti-parasite immune responses. ... -
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
(2020)A multitude of diverse microorganisms, termed the microbiota, reside in the gut, respi-ratory tract, skin, and genital tract of humans and other animals. Recent advances inmetagenomic sequencing and bioinformatics have ... -
The Role of miR-155 in Myeloid cells during Experimental Autoimmune Encephalomyelitis
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) characterised by multifocal demyelinating lesions with associated neuronal damage. Although MS is a CD4+ T cell-mediated disease, ...