Browsing by Subject "C5aR2"

Now showing items 1-2 of 2

    • C5aR2 Regulates STING-Mediated Interferon Beta Production in Human Macrophages 

      O'Neill, Luke (2023)
      The complement system mediates diverse regulatory immunological functions. C5aR2, an enigmatic receptor for anaphylatoxin C5a, has been shown to modulate PRR-dependent pro-inflammatory cytokine secretion in human macrophages. ...

    • Investigating the Signalling and Function of C5aR2 

      Wright, Oliver (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)
      Complement component 5a receptor 2 (C5aR2) is an enigmatic receptor for anaphylatoxin C5a. It was initially thought to be a decoy receptor, competitively binding to C5a to negatively regulate C5aR1 signalling. However, ...