Browsing by Subject "CYTOKINE"
Now showing items 1-2 of 2
-
IL-1 family members in health and disease
(2019)In 1985, two distinct cDNAs encoding proteins sharing human Interleukin-1 (IL-1) activity were described, thus defining the first two members of the IL-1 family – IL-1α and IL-1β. These potent pro-inflammatory cytokines ... -
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.
(2009)Th17 cells, CD4(+) T cells that secrete interleukin-17 (IL-17), are pathogenic in autoimmune diseases and their development and expansion is driven by the cytokines IL-6, TGF-beta, IL-21, IL-1, and IL-23. However, there ...