Browsing by Subject "Chitosan"
Now showing items 1-10 of 10
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Covalently cross-linked tetrafunctionalized m-THPC chitosan hydrogels as drug delivery platforms
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Photodynamic therapy (PDT) is an anti-cancer treatment method which uses the combined effect of a photosensitizing drug, light, and oxygen to cause selective damage to target tissue. The second generation photosensitizer ... -
Development of Antimicrobial Laser-Induced Photodynamic Therapy Based on Ethylcellulose/Chitosan Nanocomposite with 5,10,15,20-Tetrakis( m-Hydroxyphenyl)porphyrin
(2021)The development of new antimicrobial strategies that act more efficiently than traditional antibiotics is becoming a necessity to combat multidrug-resistant pathogens. Here we report the efficacy of laser-light-irradiated ... -
Effect of chitin, chitosan and NaCMC biopolymers on the consistency limits of organic silt
(2024)With global concerns on carbon emissions, there is increased need for various eco-friendly alternatives to conventional (cement and lime) additives used in ground improvement applications. This paper investigates the ... -
Electrospun Fibres of Chitosan/PVP for the effective chemotherapeutic drug delivery of 5-Fluorouracil
(2021)Electrospun nanofibrous mats consisting of chitosan (CS) and polyvinylpyrrolidone (PVP) were constructed. Tuning of solution and process parameters was performed and resulted in an electrospun system containing a 6:4 ... -
Engineering cartilage or endochondral bone: A comparison of different naturally derived hydrogels.
(2015)Cartilaginous tissues engineered using mesenchymal stem cells (MSCs) have been shown to generate bone in vivo by executing an endochondral programme. This may hinder the use of MSCs for articular cartilage regeneration, ... -
An Enteric-Coated Polyelectrolyte Nanocomplex Delivers Insulin in Rat Intestinal Instillations when Combined with a Permeation Enhancer
(2020)The use of nanocarriers is being researched to achieve oral peptide delivery. Insulin-associated anionic polyelectrolyte nanoparticle complexes (PECs) were formed that comprised hyaluronic acid and chitosan in an optimum ... -
Freeze drying of polyelectrolyte complex nanoparticles: Effect of nanoparticle composition and cryoprotectant selection
(2018)This work investigates the impact of nanoparticle (NP) composition and effectiveness of cryo-/lyo-protectants in a freeze drying process, which was employed to convert liquid dispersions of polyelectrolyte complex (PEC) ... -
Halloysite- and Montmorillonite-Loaded Scaffolds as Enhancers of Chronic Wound Healing
(2020)The increase in life expectancy and the increasing prevalence of diabetic disease and venous insufficiency lead to the increase of chronic wounds. The prevalence of ulcers ranges from 1% in the adult population to 3–5% in ... -
Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation
(2018)Polyelectrolyte nanoparticle constructs (NPs) comprising salmon calcitonin (sCT), chitosan (CS), and hyaluronic acid (HA) were previously established as having anti-inflammatory potential when injected via the intra-articular ... -
Mechanical behaviour of transparent nano fibrillar cellulose-chitosan nano composite films in dry and wet conditions
(2014)Transparent, biocompatible and biodegradable chitosan (CS) nanocomposite films rein- forced with nanofibrillar cellulose (NFC) were prepared by solution casting. The effects of NFC content on the mechanical properties in ...