Browsing by Subject "DNA sensing"
Now showing items 1-3 of 3
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The emerging role of human PYHIN proteins in innate immunity: Implications for health and disease.
(2014)The innate immune response depends on the ability of immune cells to detect pathogens through germline-encoded pattern recognition receptors (PRRs). Recently discovered PRRs include some members of the Pyrin and HIN domain ... -
PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells
(2020)Animal cells use pattern-recognition receptors (PRRs) to detect specific pathogens. Pathogen detection mounts an appropriate immune response, including interferon and cytokine induction. The intracellular PRR-signaling ... -
Spectroscopic and Crystallographic Evaluation of Ruthenium(II) Complexes Bearing Phenanthroline-Naphthalimide Ligands
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)Spectroscopic and Crystallographic Evaluation of Ruthenium(II) Complexes Bearing Phenanthroline-Naphthalimide Ligands Deirdre Ann McAdams This Thesis predominantly focusses on the design, synthesis, and characterisation ...