Browsing by Subject "Drug development"
Now showing items 1-4 of 4
-
Advancing the therapeutic potential of the IL-1 family in inflammatory diseases - Meeting report
(2019)On October 9th 2018 the Trinity College Dublin hosted a workshop forum at the Royal Irish Academy to discuss recent discoveries and current areas of focus in the field of IL‐1 family biology. The aim of this meeting was ... -
Preclinical Development of Orally Inhaled Drugs (OIDs)-Are Animal Models Predictive or Shall We Move Towards In Vitro Non-Animal Models?
(2020)Respiratory diseases constitute a huge burden in our society, and the global respiratory drug market currently grows at an annual rate between 4% and 6%. Inhalation is the preferred administration method for treating ... -
A promising approach to develop nanostructured lipid carriers from solid lipid nanoparticles: preparation, characterization, cytotoxicity and nucleic acid binding ability
(2020)We aimed to develop nanostructured lipid carriers (NLCs) displaying similar characteristics – particle size, polydispersity index, and zeta potential – with the model solid lipid nanoparticles (SLNs) for better comparability. ... -
Single oral dose study of two isosorbide-based aspirin prodrugs in the dog
(2003)The objective of this study was to compare two aspirin prodrugs, isosorbide diaspirinate (ISDA) and a nitroaspirin (ISMNA), with aspirin in terms of effects on dog platelet function after administration of a single oral ...