Browsing by Subject "Gout"
Now showing items 1-3 of 3
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Disease associated particulates and joint inflammation; mechanistic insights and therapeutic targets
(2018)It is now well established that intra-articular deposition of endogenous particulates, such as osteoarthritis-associated basic calcium phosphate crystals, gout-associated monosodium urate crystals, and calcium deposition ... -
Intra-articular Basic Calcium Phosphate and Monosodium Urate Crystals Inhibit anti-osteoclastogenic Cytokine Signalling
(2016)Objective: Basic calcium phosphate (BCP) and monosodium urate (MSU) crystals are particulates with potent pro-inflammatory effects, associated with osteoarthritis (OA) and gout, respectively. Bone erosion, due to increased ... -
The Pathological Associations of Hyperuricaemia in Sub-Clinical Gout, Cardiovascular and Cardiopulmonary Diseases
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Abstract - Introduction Gout is a common and treatable disease caused by the deposition of MSU crystals in articular and non-articular structures. Hyperuricaemia is the most important risk factor for the development of ...