Browsing by Subject "Leukaemia"
Now showing items 1-6 of 6
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Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo
(Nature, 2010)Background: Imatinib is a direct and potent inhibitor of the constitutively active tyrosine kinase, breakpoint cluster region-Abelson (Bcr-Abl), which is central to the pathogenesis of chronic myeloid leukaemia (CML) ... -
Understanding Acute Lymphoblastic Leukaemia
(Irish Cancer SocietyIE, 2014) -
Understanding acute lymphoblastic leukaemia
(Irish Cancer SocietyIE, 2014) -
Understanding Acute Myeloid Leukaemia
(Irish Cancer SocietyIE, 2014) -
Understanding Chronic Lymphocytic Leukaemia
(Irish Cancer SocietyIE, 2012) -
Understanding cisplatin resistance using cellular models.
(John Wiley, 2007)Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of ...