Browsing by Subject "Multiple sclerosis"
Now showing items 1-6 of 6
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Fingolimod Attenuates Splenocyte-Induced Demyelination in Cerebellar Slice Cultures
(2014)The family of sphingosine-1-phosphate receptors (S1PRs) is G-protein-coupled, comprised of subtypes S1PR1-S1PR5 and activated by the endogenous ligand S1P. The phosphorylated version of Fingolimod (pFTY720), an oral therapy ... -
Health-related quality of life in narcolepsy: A systematic review and meta-analysis
(2021)To date, there has been no systematic analysis of the literature regarding health-related quality of life in narcolepsy. This systematic review aimed to examine the impact of narcolepsy on health-related quality of life, ... -
A high-density ERP study reveals latency, amplitude, and topographical differences in multiple sclerosis patients versus controls.
(2010)Objective. To quantify latency, amplitude and topographical differences in event-related potential (ERP) components between multiple sclerosis (MS) patients and controls and to compare ERP findings with results from ... -
Impaired information processing speed and attention allocation in multiple sclerosis patients versus controls: A high-density EEG study
(2010)Background: The no-go P3a is a variant of the P300 event-related potential (ERP) that indexes speed of information processing and attention allocation. The aim of this study was to compare ERP findings with results from ... -
Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells
(2020)Interleukin-17A (IL-17A) is a major mediator of tissue inflammation in many autoimmune diseases. Anti-IL-17A is an effective treatment for psoriasis and is showing promise in clinical trials in multiple sclerosis. In this ... -
Sex differences regulate immune responses in experimental autoimmune encephalomyelitis and multiple sclerosis
(2022)MS is an autoimmune disease of the CNS that afflicts over 2.5 million people world-wide. There are striking sex differences in the susceptibility to and progression of thisdisease in humans. Females are twice as likely to ...