Browsing by Subject "Noncovalent interactions"
Now showing items 1-2 of 2
-
An Insight into Non-Covalent Interactions on the Bicyclo[1.1.1]pentane Scaffold
(2021)Bicyclo[1.1.1]pentane (BCP) is studied extensively as a bioisosteric component of drugs. Not found in nature, this molecular unit approximates the distance of a para-disubstituted benzene which is replaced in medicines as ... -
Not Your Usual Bioisostere: Solid State Study of 3D Interactions in Cubanes
(2019)Previous studies by Desiraju and co-workers have implicated the acidic hydrogen atoms of cubane as a support network for hydrogen-bonding groups. Herein we report a detailed structural analysis of all currently available ...