Browsing by Subject "Ph.D. Trinity College Dublin, 2016"
Now showing items 1-18 of 18
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A therapeutic roadmap for ovarian cancer using TLR4 MyD88 and MAD2 as prognostic indicators
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2016)Ovarian cancer is 4th leading cause of cancer death in woman and the most lethal gynaecological malignancy. Most patients present with advanced disease where the 5 year survival rate is less than 40%. Standard treatment ... -
Apologising for the inconvenience : defamiliarisation and displacement in landscapes in The Hitchiker's Guide to the Galaxy
(Trinity College (Dublin, Ireland). School of English, 2016)This thesis sought to examine worldbuilding in science fiction, and to establish whether a single driving force, named a strange attractor could be identified in an author's constructed secondary world. A theory of ... -
Ayn Rand and the posthuman : the mind-made future
(Trinity College (Dublin, Ireland). School of English, 2016)American novelist Ayn Rand's documented influence on politicians, economists, and businesspeople, makes her work an ideal case study for fiction's impact on society. This thesis considers Rand’s veneration of technological ... -
County office and county society in Dublin and Meath, c.1399 - c.1513
(Trinity College (Dublin, Ireland). Department of History, 2016)This thesis consists of a study of office-holding across two of the 'four obedient shires' of the Dublin hinterland. To attempt to compensate for the paucity of information on any individual office-holder or office-holding ... -
Estrange conflict : fragments of the Irish Troubles in the science fiction of Bob Shaw and James White
(Trinity College (Dublin, Ireland). School of English, 2016)A study of the work of the Belfast science fiction authors Bob Shaw and James White, two hitherto ignored authors in Irish Studies. Much written about Shaw and White has originated from British and American science fiction ... -
Long-term outcomes following electroconvulsive therapy for treatment-resistant depression
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2016)Background: Electroconvulsive therapy (ECT) is the most acutely effective treatment for depression but its use is limited by high rates of early relapse and retrograde amnesia of uncertain severity and duration. Aims: ... -
Losing the plot : a hermeneutic phenomenological study of the natue and meaning of psychological distress amongst third level students in Ireland
(Trinity College (Dublin, Ireland). School of Education, 2016)Psychological distress, or mental health problems, constitute the leading form of disability worldwide (World Health Organisation, 2014). While much is known about the extent, or breadth, of the issue, less is known about ... -
Origin and evolution of the Mesoarchean Aouéouat greenstone belt and associated gold mineralisation
(Trinity College (Dublin, Ireland). Department of Geology, 2016)This Aouéouat greenstone belt is situated in the Tasiast-Tijirit Terrane of the Reguibat Shield, part of the West African Craton. Petrographic, geochronological, geochemical and isotopic studies of the Aouéouat greenstone ... -
Perceptions and uses of Gothic in Irish domestic and ecclesiastical architecture, 1800 - 1815
(Trinity College (Dublin, Ireland). Department of History of Art and Architecture, 2016)Perceptions of Gothic in the late eighteenth and early nineteenth century, and its use in domestic and ecclesiastical architecture in Ireland, 1800-1841' is a study of meaning in Gothic revival architecture. The thesis ... -
"Say it simply [...] say it simplier" : Samuel Beckett and Gertrude Stein's aesthetics of writing worser
(Trinity College (Dublin, Ireland). School of English, 2016)While critics have long acknowledged the critical importance of Samuel Beckett's expressed desire in the Axel Kaun letter, dated July 9 1937, to tear at language as an indication of his changing aesthetics, they have tended ... -
Support measures for child witnesses in criminal proceedings in Ireland
(Trinity College (Dublin, Ireland). School of Law, 2016)Recent constitutional, legislative and cultural changes have encompassed a significant restructuring of the rights framework for the child in Irish society. This thesis explores how this has affected the child witness in ... -
Tailored nitrogen-containing polyaromatics - from surfaces to stacks
(Trinity College (Dublin, Ireland). School of Chemistry, 2016)Chapter 1: This chapter gives a broad introduction to the subjects of graphene and nanographenes, which are discussed in subsequent chapters. Common methodologies for the synthesis of substituted polyphenylenes and ... -
That awful secret of the wood' : the forest and the EcoGothic
(Trinity College (Dublin, Ireland). School of English, 2016)When we imagine the forest, we tend towards extremes. It is commonly read as a binary space: as either ‘good’ or ‘bad’. When it is ‘good’, it is a remedial setting of wonder and enchantment; when it is ‘bad’, it is a ... -
The beauty of the Grotesque : a history and semiotics of serifless typefaces
(Trinity College (Dublin, Ireland). Centre for Language and Communication Studies, 2016)This is a study of a style of typeface - the Grotesque - and a way of thinking about this style that was central to twentieth-century typographic discourse. It traces both the development of Grotesque styles, and the ... -
The evolving character of the French Reformed Movement, c.1555 - c.1572
(Trinity College (Dublin, Ireland). Department of History, 2016) -
The impact of the Great War on women in Ireland, 1914 - 1919
(Trinity College (Dublin, Ireland). Department of History, 2016)The impact of the Great War on women is a significant area of scholarship within First World War studies. The legacy of the war for women's lives and role in society has been the subject of much debate. This thesis ... -
The Irish Hydra : English policy and plantations in Gaelic Ulster in 1567 - 79
(Trinity College (Dublin, Ireland). Department of History, 2016)The aim of this thesis is provide an analysis of Ulster politics during the period between the death of Shane O'Neill in June 1567 and the Crown's estrangement from Turlough Luineach O'Neill in 1579. The importance of this ... -
The zircon record of the Sudbury impact crater and its implications for the early Earth
(Trinity College (Dublin, Ireland). Department of Geology, 2016)In the absence of widespread rocks older than 4.0 Ga, the earliest terrestrial material and the only direct evidence for the nature of the Earth's very early crust are tiny zircon crystals. The chemical compositions of ...