Browsing by Subject "Small Cell Lung Cancer"
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ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair.
(Springer Verlag, 2009)Background: The H69CIS200 and H69OX400 cell lines are novel models of low- level platinum-drug resistance. Resistance was not associated with increased cellular glutathione or decreased accumulation of platinum, rather ... -
Oxaliplatin induces drug resistance more rapidly than cisplatin in H69 small cell lung cancer cells
(Springer, 2006)Cisplatin produces good responses in solid tumours including small cell lung cancer (SCLC) but this is limited by the development of resistance. Oxaliplatin is reported to show activity against some cisplatin-resistant ...