Browsing by Subject "Systemic inflammation"
Now showing items 1-3 of 3
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Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms
(2018)Systemic inflammation can impair cognition with relevance to dementia, delirium and post-operative cognitive dysfunction. Episodes of delirium also contribute to rates of long-term cognitive decline, implying that these ... -
Double stranded RNA drives anti-viral innate immune responses, sickness behavior and cognitive dysfunction dependent on dsRNA length, IFNAR1 expression and age
(2021)Double stranded RNA is generated during viral replication. The synthetic analogue poly I:C is frequently used to mimic anti-viral innate immune responses in models of psychiatric and neurodegenerative disorders ... -
Interactions Between Systemic Inflammation, Frailty And Neuroinflammation In Ageing And Neurodegeneration
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2022)Compelling evidence continues to define the pivotal role which inflammation plays in the progression of neurodegenerative diseases and ageing. It has emerged that inflammation outside the brain significantly contributes ...