Browsing by Subject "Thiol-ene"

Now showing items 1-2 of 2

    • Development of Novel Acyl Thiol-ene Mediated Peptide Ligation Strategies 

      Mclean, Joshua Timothy (Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)
      This thesis, entitled Development of Novel Acyl Thiol-ene Mediated Peptide Ligation Strategies is composed of six chapters. Chapter 1 provides an introductory overview of the fields of amide synthesis and peptide ligation. ...

    • Novel Approaches to Probe the Activity of Deubiquitinating Enzymes 

      Taylor, Neil (Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)
      Ubiquitination is a highly conserved post-translational modification that regulates a multitude of critical cellular events. This process is orchestrated by a complex enzymatic network. Deubiquitinating enzymes (DUBs) ...