Browsing by Subject "Vitamin D"
Now showing items 1-15 of 15
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Association between low serum vitamin d and Increased mortality and severity due to COVID-19: reverse causality?
(2022)We are very close to completing two years since the start of the COVID-19 pandemic. Even though vaccines have been developed and applied to more than 4 billion people in the world, SARS-CoV-2 continues to be a challenge ... -
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.
(2014)BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation ... -
Autophagy in the immune response to tuberculosis: clinical perspectives
(2011)A growing body of evidence points to autophagy as an essential component in the immune response to tuberculosis. Autophagy is a direct mechanism of killing intracellular Mycobacterium tuberculosis and also acts as a modulator ... -
Dose-related effects of vitamin D on immune responses in patients with clinically isolated syndrome and healthy control participants: study protocol for an exploratory randomized double- blind placebo-controlled trial.
(2013)Background There is increasing evidence linking vitamin D deficiency to both susceptibility to, and severity of, multiple sclerosis (MS). Patients with the clinically isolated syndrome represent the initial presentation ... -
Functional Relevance of Interleukin 8 Haplotype for the Innate Immune System in Holstein-Friesian Cattle
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2021)Calves rely heavily on their innate immune response in the post-birth period before their adaptive immune system develops. Interleukin 8 (IL-8) is a major chemoattractant predominantly associated with neutrophils response ... -
Innate immune phenotype variation in bovine health and disease
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Infectious diseases are estimated to cost the global agriculture industry $300 billion annually and present significant challenges to animal welfare. Disease burden in cattle and other livestock species also threaten ... -
Perspective: Vitamin D supplementation prevents rickets and acute respiratory infections when given as daily maintenance but not as intermittent bolus: Implications for COVID-19
(2021)The value of vitamin D supplementation in the treatment or prevention of various conditions is often viewed with scepticism as a result of contradictory results of randomised trials. It is now becoming apparent that there ... -
Preventing vitamin D deficiency during the COVID-19 pandemic: UK definitions of vitamin D sufficiency and recommended supplement dose are set too low
(2021)There is growing evidence linking vitamin D deficiency with risk of COVID-19. It is therefore distressing that there is major disagreement about the optimal serum level for 25-hydroxyvitamin D (25(OH)D) and appropriate ... -
The role of vitamin D and UVB on the risk and survival of oesophageal and gastric cancer
(Trinity College Dublin. School of Medicine. Discipline of Public Health & Primary Care, 2018)The Role of Vitamin D and UVB on the Risk and Survival of Oesophageal and Gastric Cancer By Fiona O?Sullivan Background: Vitamin D is a fat-soluble vitamin which has many sources. Currently, there are numerous ways in ... -
Severity and Mortality of SARS-COV-2 infection and 25-hydroxyvitamin D concentration: a metanalysis
(2021)Introduction: There is increasing scientific interest in the possible association between hypovitaminosis D and the risk of SARS-CoV-2 infection severity and/or mortality. Objective: To conduct a metanalysis of the ... -
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials.
(2014)OBJECTIVE: To evaluate the breadth, validity, and presence of biases of the associations of vitamin D with diverse outcomes. DESIGN: Umbrella review of the evidence across systematic reviews and meta-analyses of ... -
Vitamin D and orthostatic hypotension.
(2012)Introduction: we aimed to investigate on the potential relationship between vitamin D and orthostatic hypotension (OH) in a case-control model in older adults. Methods: all participants were community-dwelling adults who ... -
Vitamin D in ageing: an investigation into the role of vitamin D in cognitive and physical functioning in coummunity-dwelling older adults
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2018)With our growing older population, there is an increasing need to identify potentially modifiable characteristics or interventions that are intended to enhance the functioning of older adults who could be described as ... -
Vitamin D in the elderly and its relationship to inflammation and cognitive health
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)Background: There is a major shift in ageing demographics as individuals are experiencing increased longevity. This shift may be beneficial for the individual who will live into more advanced year than their ancestors. ... -
Vitamin D in the Irish Population: an analysis of prevalence and determinants
(Trinity College Dublin. School of Medicine. Discipline of Public Health & Primary Care, 2023)Introduction: Vitamin D has an established role in bone and muscle health, with deficiency causing rickets in children, osteomalacia in adults and contributing to the development of osteoporosis. More recently it has been ...