Browsing by Subject "azetidinone ring scaffold"
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Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones
(2011)A series of azetidin-2-ones substituted at positions 2, 3 and 4 of the azetidinone ring scaffold were synthesised and evaluated for antiproliferative, cytotoxic and tubulin binding activity. In these compounds, the cis ...