Browsing by Subject "coeliac disease"
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Alpha gliadin antibody levels: a serological test for coeliac disease.
(1983)The diagnostic value in coeliac disease of circulating antibodies to casein, crude gliadin, and alpha gliadin was assessed using an adaption of the enzyme linked immunosorbent assay system. alpha Gliadin was the only antigen ... -
Association of clinical phenotype and genetic burden in coeliac disease
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2018)Coeliac disease (CD) is a chronic small intestinal immune-mediated enteropathy precipitated by exposure to a gluten containing diet in genetically predisposed individuals. The clinical presentation of CD is highly ... -
Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study
(2010)BACKGROUND: Recent whole genome analysis and follow-up studies have identified many new risk variants for coeliac disease (CD, gluten intolerance). The majority of newly associated regions encode candidate genes with a ... -
Humoral response to wheat protein in patients with coeliac disease and enteropathy associated T cell lymphoma.
(1986)Features that might distinguish uncomplicated coeliac disease from enteropathy associated T cell lymphoma were investigated. Of 76 patients with coeliac disease, 71 (93%) had raised levels of alpha gliadin antibody and all ... -
Protein kinase C delta is a substrate of tissue transglutaminase and a novel autoantigen in coeliac disease
(2013)Post-translational modification of proteins by deamidation or transamidation by tissue transglutaminase (tTG) has been suggested as a possible mechanism for the development of autoimmunity. Sequence analysis of protein ...