Browsing by Subject "cytokine"
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Antiviral activity of human hepatocytes and its regulation by cellular antioxidant systems
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Although several antiviral strategies have been developed in the last decade, hepatotropic viruses are still a significant public health burden, with more than 300 million people being affected worldwide. Hepatocytes, the ... -
Autophagy and inflammatory diseases.
(2013)Autophagy is a cellular mechanism for the sequestration and degradation of intracellular pathogens and compromised organelles, particularly damaged mitochondria. Autophagy also clears other cellular components, such as ... -
IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
(2014)Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models ...