Browsing by Subject "glucose, 50-99-7, 84778-64-3; glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; insulin, 9004-10-8; insulin receptor substrate 2, 223747-03-3; phosphatidylinositol 3 kinase, 115926-52-8; protein kinase B, 148640-14-6; somatomedin C, 67763-96-6;Insulin Receptor Substrate Proteins; Irs2 protein, mouse; Receptors, N-Methyl-D-Aspartate"
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Brain deletion of insulin receptor substrate 2 disrupts hippocampal synaptic plasticity and metaplasticity
(2012)Objective: Diabetes mellitus is associated with cognitive deficits and an increased risk of dementia, particularly in the elderly. These deficits and the corresponding neurophysiological structural and functional alterations ...