Browsing by Subject "inflammatory bowel disease"
Now showing items 1-4 of 4
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Editorial: low population mortality from COVID-19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity
(2020)The excellent review by Al-Ani et al reflects a consensus approach to management of inflammatory bowel disease during the SARS-CoV-2 pandemic that has been established remarkably rapidly by very effective international ... -
Evaluating the role of angiogenesis in disease behaviour and therapy response in ulcerative colitis
Introduction Ulcerative colitis (UC) is a chronic inflammatory condition with a significant impact on quality of life. In this thesis two small molecule anti-angiogenic and anti-inflammatory agents were used to treat tissue ... -
Intestinal targeting of small molecule MMP and TGR5 ligands for inflammatory bowel disease
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2018)The aetiology of inflammatory bowel disease (IBD) is incompletely understood but it is generally accepted to involve a dysregulated intestinal immune response to commensal microbiota and an increase in intestinal permeability. ... -
Matrix metalloproteinase-9 modulates intestinal injury in rats with transmural colitis.
(2006)Proteolysis and degradation of extracellular matrix by metalloproteinases (MMPs) may contribute to intestinal injury in inflammatory bowel disease. In the present study, we investigated the pathogenic role of gelatinases ...