Browsing by Subject "myeloid cells"
Now showing items 1-2 of 2
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Investigation of Staphylococcus aureus-induced immunosuppression during nasal colonisation and the implications for vaccine function
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Staphylococcus aureus (S. aureus) is a major part of the natural human microbiome, primarily colonising the anterior nares. The overall aim of this project was to determine the impacts nasal colonisation has on local and ... -
mTOR- and HIF-1¿-mediated aerobic glycolysis as metabolic basis for trained immunity.
(2014)Epigenetic reprogramming of myeloid cells, also known as trained immunity, confers nonspecific protection from secondary infections. Using histone modification profiles of human monocytes trained with the Candida albicans ...