Browsing by Subject "psoriasis"
Now showing items 1-3 of 3
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Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis
(2011)Objectives: To investigate a shared genetic aetiology for skin involvement in psoriasis and psoriatic arthritis (PsA) by genotyping single-nucleotide polymorphisms (SNPs), reported to be associated in genome-wide ... -
Harnessing the therapeutic properties of the Heme Oxygenase system
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)The stress response enzyme, Heme Oxygenase 1 (HO-1), has been identified as an important immunomodulator which is highly upregulated in response to cellular stress and inflammation. HO-1 catalyses the conversion of free ... -
Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis
(2010)Objective: A common deletion mapping to the psoriasis susceptibility locus 4 on chromosome 1q21, encompassing two genes of the late cornified envelope (LCE) gene cluster, has been associated with an increased risk of ...