Browsing Pharmacy and Pharmaceutical Sciences (Scholarly Publications) by Title
Now showing items 21-40 of 445
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Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil
(2016)Zanthoxylum piperitum DC. (ZP) is a traditional medicinal plant used mainly in countries from Asia such as Japan. This study aimed to investigate the antinociceptive effect of ZP essential oil (ZPEO).Themajor component ... -
Antioxidant activity from the leaf extracts of Jacaranda puberula Cham., Bignoniaceae, a Brazilian medicinal plant used for blood depuration
(2010)The antioxidant activity of leaf extracts from Jacaranda puberula Cham., Bignoniaceae, was assayed by the DPPH (2,2-diphenyl-1-picryl-hydrazyl) free radical scavenging method. Three phytomedicines (F1, F2, and F3) used as ... -
The antiviral potential of algal-derived macromolecules
(2021)A diverse range of molecules with anticancer, antiviral, and antibiotic activities has been identified and isolated from algal species. Such metabolites could address unmet clinical needs and be used to fight human diseases. ... -
Approaches to the safety assessment of engineered nanomaterials (ENM) in food
(Elsevier, 2011)A systematic, tiered approach to assess the safety of engineered nanomaterials (ENMs) in foods is presented. The ENM is first compared to its non-nano form counterpart to determine if ENM-specific assessment is required. ... -
Assessment of renal function in the anaesthetised rat following injection of superparamagnetic iron oxide nanoparticles
(2017)A recent study showed that a significant fall in mean arterial pressure (MAP) occurred following intravenous injection of two novel superparamagnetic iron oxide nanoparticles (SPIONs), MF66 and OD15. To assess if this was ... -
Association of Anticholinergic burden with adverse effects in older people with Intellectual Disabilities in Ireland: An observational cross-sectional study
(2016)Background:Older people with intellectual disabilities (ID) receive anticholinergic drugs but no studies to date have investigated cumulative anticholinergic exposure and its effects in adults with ID. Aim: To determine ... -
Barriers and facilitators of medicines reconciliation at transitions of care in Ireland - a qualitative study
(2020)Background: Medication error at transitions of care is common. The implementation of medicines reconciliation processes to improve this issue has been recommended by many regulatory and safety organisations. The aim of ... -
Baseline study of Community Pharmacy Practice in Ireland - report
(Pharmaceutical Society of Ireland, 2011) -
Benzodiazepine usage in the North Eastern Health Board region of the Republic of Ireland
(2004)Introduction: Benzodiazepines are a large group of drugs used as hypnotics, anxiolytics, and tranquillisers, anti convulsants, pre-medication and for intravenous sedation. Extended use of benzodiazepines may lead to ... -
Bioactive Indanes: Development and validation of an LC-MS/MS bioanalytical method for the determination of PH46A, a new potential anti-inflammatory agent, in dog and rat plasma and its application to a pharmacokinetic study in dog.
(2020)A new chemical entity, which is a chiral indane dimer, PH46A, has been developed by our research group. As a clinical candidate. PH46A has recently completed Phase I clinical studies in man. Previously, during its pre-clinical ... -
Biocompatible copolymer formulations to treat glioblastoma multiforme.
(2021)The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years while the prognosis for the patients is still poor and most of them survive less than 1 year after diagnosis. The standard of care for ...