dc.contributor.author | CONNON, STEPHEN | en |
dc.contributor.author | GUNDALA , SIVAJI | en |
dc.date.accessioned | 2011-11-18T14:57:36Z | |
dc.date.available | 2011-11-18T14:57:36Z | |
dc.date.issued | 2011 | en |
dc.date.submitted | 2011 | en |
dc.identifier.citation | S. E. O'Toole, C. A. Rose, S. Gundala, K. Zeitler and S. J. Connon, Highly chemoselective direct crossed aliphatic- aromatic acyloin condensations with triazolium-derived carbene catalysts, Journal of Organic Chemistry, 76, 2, 2011, 347-357 | en |
dc.identifier.other | Y | en |
dc.identifier.uri | http://hdl.handle.net/2262/60820 | |
dc.description | PUBLISHED | en |
dc.description.abstract | It has been shown for the first time that triazolium pre-catalysts promote (in the
presence of base) highly chemoselective crossed acyloin condensation reactions between
aliphatic and ortho-substituted aromatic aldehydes. An o-bromine atom can serve as a
temporary directing group to ensure high chemoselectivity (regardless of the nature of the
other substituents on the aromatic ring) which then can be conveniently removed. The
process is of broad scope and is operationally simple as it does not require the preactivation
of any of the coupling partners to ensure selectivtiy. Preliminary data indicates
that highly enantioselective variants of the reaction are feasible using chiral pre-catalysts. | en |
dc.description.sponsorship | This work emanates from a study funded by Science Foundation Ireland (SFI).
Financial support of the DFG (Deutsche Forschungsgemeinschaft) and the Irish Research Council for
Science Engineering and Technology are gratefully acknowledged. | en |
dc.format.extent | 347-357 | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Journal of Organic Chemistry | en |
dc.relation.ispartofseries | 76 | en |
dc.relation.ispartofseries | 2 | en |
dc.rights | Y | en |
dc.subject | Chemistry | en |
dc.subject | enantioselective | en |
dc.title | Highly chemoselective direct crossed aliphatic- aromatic acyloin condensations with triazolium-derived carbene catalysts | en |
dc.type | Journal Article | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/connons | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/gundalas | en |
dc.identifier.rssinternalid | 71050 | en |
dc.subject.TCDTheme | Nanoscience & Materials | en |
dc.identifier.rssuri | http://dx.doi.org/10.1021/jo101791w | en |
dc.contributor.sponsor | Science Foundation Ireland (SFI) | en |
dc.contributor.sponsor | Irish Research Council for Science and Engineering Technology (IRCSET) | en |