dc.contributor.author | KELLY, JOHN MOFFAT | |
dc.contributor.author | WILLIAMS, DAVID CLIVE | |
dc.contributor.author | GUNNLAUGSSON, THORFINNUR | |
dc.date.accessioned | 2013-12-11T09:56:08Z | |
dc.date.available | 2013-12-11T09:56:08Z | |
dc.date.issued | 2013 | |
dc.date.submitted | 2013 | en |
dc.identifier.citation | Banerjee S, Kitchen JA, Bright SA, O'Brien JE, Williams DC, Kelly JM, Gunnlaugsson T, Synthesis, spectroscopic and biological studies of a fluorescent Pt(ii) (terpy) based 1,8-naphthalimide conjugate as a DNA targeting agent., Chemical communications (Cambridge, England), 49, 76, 2013, 8522-8524 | en |
dc.identifier.other | Y | |
dc.identifier.uri | http://hdl.handle.net/2262/67730 | |
dc.description | PUBLISHED | en_US |
dc.description.abstract | The bi-functional complex [PtII(terpy)(py-naphth)](NO 3)2(1), incorporating both 2,2?:6?, 2??-terpyridine and 4-N,N?-dimethylamino-1,8-naphthalimide moieties, displays a high binding affinity for DNA as well as displaying cytotoxicity towards and inducing apoptosis in malignant cell lines. | en_US |
dc.description.sponsorship | We would like to thank CSCB, PRTLI Cycle 4 (TG and JMK),
TCD (Scholarship to SB and Finical Support to SAB and DCW),
IRCSET (JAK Postdoctoral Fellowship) and SFI PI 2010 grant
(TG) for financial support | en_US |
dc.format.extent | 8522-8524 | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | Chemical communications (Cambridge, England); | |
dc.relation.ispartofseries | 49; | |
dc.relation.ispartofseries | 76; | |
dc.rights | Y | en |
dc.subject | DNA | en_US |
dc.title | Synthesis, spectroscopic and biological studies of a fluorescent Pt(ii) (terpy) based 1,8-naphthalimide conjugate as a DNA targeting agent. | en |
dc.type | Journal Article | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/jmkelly | |
dc.identifier.peoplefinderurl | http://people.tcd.ie/dwillims | |
dc.identifier.peoplefinderurl | http://people.tcd.ie/gunnlaut | |
dc.identifier.rssinternalid | 87898 | |
dc.rights.ecaccessrights | OpenAccess | |