Ruthenium(11) metal complexes for photodynamic therapy (PDT) or as imaging agents
Citation:
Marialuisa Erby, 'Ruthenium(11) metal complexes for photodynamic therapy (PDT) or as imaging agents', [thesis], Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2013, pp 314Download Item:
Abstract:
Photodynamic therapy (PDT) represents a new localised method of treatment in cancer.
The therapeutic effect is mediated by the generation of reactive oxygen species (ROS)
and/or the formation of singlet oxygen (1 O2), a process that depends on the photosensitizing agent's interactions with light and oxygen. The photophysical and DNA binding properties of a cationic water-soluble organic derivate of dppz, has previously been reported and its suitability for PDT has been suggested.
Author: Erby, Marialuisa
Advisor:
Williams, DCQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of Biochemistry and ImmunologyNote:
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