The Red Color of Life Transformed – Synthetic Advances and Emerging Applications of Protoporphyrin IX in Chemical Biology
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Mathias Senge, 'The Red Color of Life Transformed – Synthetic Advances and Emerging Applications of Protoporphyrin IX in Chemical Biology', 2020, European Journal of Organic Chemistry;Download Item:
Abstract:
Protoporphyrin IX (PPIX) is the porphyrin scaffold of
heme b, a ubiquitous prosthetic group of proteins responsible
for oxygen binding (hemoglobin, myoglobin), electron transfer
(cytochrome c) and catalysis (cytochrome P450, catalases, per-
oxidases). PPIX and its metallated derivatives frequently find
application as therapeutic agents, imaging tools, catalysts, sen-
sors and in light harvesting. The vast toolkit of accessible por-
phyrin functionalization reactions enables easy synthetic
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https://chemistry-europe-onlinelibrary-wiley-com.elib.tcd.ie/doi/full/10.1002/ejoc.202000074http://hdl.handle.net/2262/95396
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Science Foundation Ireland
IvP 13/IA/1894
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http://people.tcd.ie/sengem
Author: Senge, Mathias
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https://chemistry-europe-onlinelibrary-wiley-com.elib.tcd.ie/doi/full/10.1002/ejoc.202000074http://hdl.handle.net/2262/95396
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European Journal of Organic Chemistry;Availability:
Full text availableKeywords:
myoglobin, therapeutic agents, hemoglobinDOI:
https://doi-org.elib.tcd.ie/10.1002/ejoc.202000074Metadata
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