Prolonged oral coenzyme Q10-β-cyclodextrin supplementation increases skeletal muscle complex I+III activity in young Thoroughbreds

Abstract

In summary, this study demonstrated that oral supplemen- tation of young, healthy untrained Thoroughbreds on a pasture and oat diet with a CoQ 10 -β-cyclodextrin inclusion complex via syringe significantly increased mean plasma CoQ 10 concentrations. Prolonged daily supplementation also increased skeletal muscle CoQ 10 content, although a degree of variability was identified for some horses. Additional research is warranted to investigate the effects of MSTN genotype, training and exercise on skeletal muscle CoQ 10 content in CoQ 10 -β-cyclodextrin inclusion complex supplemented and un-supplemented Thoroughbreds