Browsing by Author "Martin, Cara"
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Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice.
O'Toole, Sharon; O'Neill, Luke; Martin, Cara (2020)Influenza A virus (IAV) infection during pregnancy causes severe maternal and perinatal complications, despite a lack of vertical transmission of IAV across the placenta. Here, we demonstrate a significant alteration in ... -
Molecular characterisation of a new variant of inflammatory bowel disease in children with autism
Martin, Cara (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2004)A new variant of inflammatory bowel disease, provisionally termed "autistic enterocolitis" has been described in a cohort of children with autistic spectrum disorders. The intestinal pathology includes ileo-colonic ... -
Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening.
Norris, Lucy; Martin, Cara; O'Leary, John; Finn, Stephen; O'Toole, Sharon; Sheils, Orla; Abu Saadeh, Feras; Flavin, Richard; Kelly, Lynne (2013)Platinum resistance is a major cause of treatment failure in ovarian cancer. We previously identified matrix metalloproteinase 9 (MMP-9) as a potential therapeutic target of chemoresistant disease. A2780cis (cisplatin-resistant) ...