Molecular characterisation of a new variant of inflammatory bowel disease in children with autism
Citation:
Cara Martin, 'Molecular characterisation of a new variant of inflammatory bowel disease in children with autism', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2004, pp 359Abstract:
A new variant of inflammatory bowel disease, provisionally termed "autistic enterocolitis" has been described in a cohort of children with autistic spectrum
disorders. The intestinal pathology includes ileo-colonic lymphonodular hyperplasia and non-specific colitis, which lacks the specific diagnostic features of Crohn's
disease or ulcerative colitis. The level of gastrointestinal dysfunction in these children is poorly understood and studies to date have focused primarily on macroscopic and microscopic features of the condition. In addition, the aetiology remains unknown, although an association between measles virus infection or vaccination, onset of gastrointestinal symptoms and developmental regression in these children, has been speculated.
Author: Martin, Cara
Advisor:
O'Leary, JohnQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid AnatomyNote:
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