Browsing by Subject "Hypoxia"
Now showing items 1-5 of 5
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Deciphering the interplay of extracellular vesicles and drug resistance in HER2-positive breast cancer: insights, biomarkers and therapeutic implications
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)According to a World Health Organisation (WHO) report on 3rd March 2021, breast cancer is the most common form of cancer in the world and the leading cause of cancer death among females. In 2020, 2.26 million newly breast ... -
?Examining the connectivity between different cellular processes in the Barrett tissue microenvironment: energy metabolism, hypoxia, inflammation, p53 and obesity?.
(2016)In Barrett associated tumorigenesis, oxidative phosphorylation and glycolysis are reprogrammed early in the disease sequence and act mutually to promote disease progression. However, the link between energy metabolism and ... -
Hypoxia mimicking hydrogels to regulate the fate of transplanted stem cells
(2019)Controlling the phenotype of transplanted stem cells is integral to ensuring their therapeutic efficacy. Hypoxia is a known regulator of stem cell fate, the effects of which can be mimicked using hypoxia-inducible factor ... -
The role of energy metabolism in driving disease progression in inflammatory, hypoxic and angiogenic environments
(2015)Cellular metabolism plays a crucial role in primed inflammatory, hypoxic and an - giogenic microenvironments by supporting disease progression in a range of disease entities. To adapt to fluctuating st ... -
?The role of energy metabolism in driving disease progression in inflammatory, hypoxic and angiogenic microenvironments'.
(2015)Cellular metabolism plays a crucial role in primed inflammatory, hypoxic and angiogenic microenvironments by supporting disease progression in a range of disease entities. To adapt to fluctuating stress-induced ...