Browsing Chemistry (Theses and Dissertations) by Title
Now showing items 73-92 of 398
-
Design, synthesis, photophysical and biological evaluation of Novel 1,8-naphthalimide derivatives as DNA binders and potential anti-cancer agents
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)This thesis, titled 'Design, Synthesis, Photophysical and Biological Evaluation of Novel 1,8-Naphthalimide Derivatives As DNA Binders and Potential Anti-Cancer Agents' is divided into seven chapters. The first chapter is ... -
Designer Nonplanar Porphyrins with Tuned Properties for Application as Bifunctional Organocatalyst
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)The aim of this research was to investigate the use of different free base nonplanar porphyrins as bifunctional catalysts. This involved the tailored design of various porphyrin catalysts and the subsequent testing of said ... -
Developing 1,10-phenanthroline complexes towards their application as triplet sensitizers
(Trinity College (Dublin, Ireland). School of Chemistry, 2014)Summary - Chapter 1: This chapter begins with a general introduction to polycyclic aromatic hydrocarbons, followed by a focused review of recent 3,8-substituted 1,10-phenanthroline systems reported in the literature. The ... -
Developing state of the art sample preparation for high-resolution electron microscopy
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)In recent years there have been great advances in scanning transmission electron microscopes, in particular, high-resolution low voltage imaging and high-resolution electron energy loss spectroscopy. These techniques rely ... -
Development and investigation of novel transition metal mediated reactions in porphyrin chemistry
(Trinity College (Dublin, Ireland). School of Chemistry, 2009)The aim of this work was to extend the number of existing pathways for the synthesis of porphyrins. The focus was directed towards the development and investigation of new transition metal catalysed reactions in porphyrin ... -
Development and Studies of New Magnetic Core@Shell Nanostructures
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)In this work, the synthesis of various magnetic nanoparticles such as magnetite, manganese ferrite, cobalt ferrite and copper ferrite is explored using different synthetic protocols. The produced nanomaterials are characterised ... -
Development of 2D Nanomaterials Based Membranes for Nanofiltration Applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)The main aim of this work was to develop new membranes based on 2D nanomaterials, such as boron nitride (BN) and molybdenum disulphide (MoS2) for potential nanofiltration applications. The exfoliation and membrane preparation ... -
Development of a robust throughput process for the production of PMMA membranes via a TIPS air casting method
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Lateral flow membranes (membranes that allow movement of fluid across the membrane rather than through it) play a crucial role in the functionality of immunoassay devices determining performance speed and assay reliability. ... -
Development of a Scaleable Breath-figure Type Polymer Thin Film Patterning Process via Controlled Vapour Swelling of Thin Films
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)Efficient production of microporous polymeric films can be rapidly synthesised by changing the thermodynamics of a polymeric solution in a humid atmosphere. This conventional method, known as ?breath figure? (BF), involves ... -
Development of a solution-based process for hydroxyapatite and functionalised hydroxyapatite
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Hydroxyapatite coatings have long been established as a means of improving the osteointegration of metallic orthopaedic implants. Nonetheless there are both technical and commercial drawbacks associated with industrial ... -
Development of Calcium Carbonate-based Nano- and Micro- Structural Materials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)Calcium carbonate is a ubiquitous material, which has a high commercial importance and a variety of important applications. The main goal of this work is the development of new CaCO3 based nano- and micro-structural materials ... -
Development of chiral nanoparticles
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)Symmetry and chirality are common occurrences in the natural world. Chiral compounds are extremely important in chemistry, biology and medicine. Chirality has also been envisaged to play an important role in nanotechnology. ... -
Development of Cu-based multicomponent quantum nanostructures
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)The main goal of this project was to develop novel Cu-based multicomponent quantum nanostructures with distinct morphologies and optical properties and explore their potential applications as materials for luminescent solar ... -
Development of Enantioselective Processes Catalysed by Novel Asymmetric Bifunctional Phase-Transfer Organocatalysts
A new family of chiral bifunctional phase-transfer catalysts were developed to promote an enantioselective SN2 reaction for the construction of malleable oxindoles with all-carbon quaternary stereocenters in high yield and ... -
Development of modified nucleosides for targeting the DNA repair enzyme SNM1A
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Certain cancers exhibit upregulation of DNA interstrand crosslink repair pathways, which contributes to resistance to crosslinking chemotherapy drugs and poor prognoses. Inhibition of enzymes implicated in interstrand ... -
Development of Multimodal Magnetic-Plasmonic Nanocomposites
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)The main aim of this work was to prepare a wide range of magnetic-plasmonic nano- and micro-materials and to explore their properties and potential applications. The combination of both magnetic and plasmonic properties ... -
Development of new 1D metal based nanomaterials: Synthesis, charaterisation and applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2019)The main aim of this project was to develop new 1D metal based nanomaterials and explore their use for potential applications in catalysis. This work involves the synthesis, characterisation, and application of new AuAg ... -
Development of new silica and magnetic-luminescent silica nanostructured materials
(Trinity College (Dublin, Ireland). School of Chemistry, 2011)The main aim of this project is to develop a series of nanocomposite materials based on silica and magnetic-luminescent silica nanoparticles. The work involves the synthesis and characterisation of silica nanoparticles, ... -
Development of Novel Acyl Thiol-ene Mediated Peptide Ligation Strategies
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)This thesis, entitled Development of Novel Acyl Thiol-ene Mediated Peptide Ligation Strategies is composed of six chapters. Chapter 1 provides an introductory overview of the fields of amide synthesis and peptide ligation. ... -
Development of novel organocatalysts towards the kinetic and dynamic resolution of chiral enolisable anhydrides
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2018)In this thesis we explore the possibilities offered by the bifunctional properties of a series of organocatalysts derived from cinchona alkaloids for the promotion of novel asymmetric transformations. In particular, we ...