Browsing Chemistry (Theses and Dissertations) by Title
Now showing items 83-102 of 398
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Development of Calcium Carbonate-based Nano- and Micro- Structural Materials
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)Calcium carbonate is a ubiquitous material, which has a high commercial importance and a variety of important applications. The main goal of this work is the development of new CaCO3 based nano- and micro-structural materials ... -
Development of chiral nanoparticles
(Trinity College (Dublin, Ireland). School of Chemistry, 2008)Symmetry and chirality are common occurrences in the natural world. Chiral compounds are extremely important in chemistry, biology and medicine. Chirality has also been envisaged to play an important role in nanotechnology. ... -
Development of Cu-based multicomponent quantum nanostructures
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)The main goal of this project was to develop novel Cu-based multicomponent quantum nanostructures with distinct morphologies and optical properties and explore their potential applications as materials for luminescent solar ... -
Development of Enantioselective Processes Catalysed by Novel Asymmetric Bifunctional Phase-Transfer Organocatalysts
A new family of chiral bifunctional phase-transfer catalysts were developed to promote an enantioselective SN2 reaction for the construction of malleable oxindoles with all-carbon quaternary stereocenters in high yield and ... -
Development of modified nucleosides for targeting the DNA repair enzyme SNM1A
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Certain cancers exhibit upregulation of DNA interstrand crosslink repair pathways, which contributes to resistance to crosslinking chemotherapy drugs and poor prognoses. Inhibition of enzymes implicated in interstrand ... -
Development of Multimodal Magnetic-Plasmonic Nanocomposites
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)The main aim of this work was to prepare a wide range of magnetic-plasmonic nano- and micro-materials and to explore their properties and potential applications. The combination of both magnetic and plasmonic properties ... -
Development of new 1D metal based nanomaterials: Synthesis, charaterisation and applications
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2019)The main aim of this project was to develop new 1D metal based nanomaterials and explore their use for potential applications in catalysis. This work involves the synthesis, characterisation, and application of new AuAg ... -
Development of new silica and magnetic-luminescent silica nanostructured materials
(Trinity College (Dublin, Ireland). School of Chemistry, 2011)The main aim of this project is to develop a series of nanocomposite materials based on silica and magnetic-luminescent silica nanoparticles. The work involves the synthesis and characterisation of silica nanoparticles, ... -
Development of Novel Acyl Thiol-ene Mediated Peptide Ligation Strategies
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)This thesis, entitled Development of Novel Acyl Thiol-ene Mediated Peptide Ligation Strategies is composed of six chapters. Chapter 1 provides an introductory overview of the fields of amide synthesis and peptide ligation. ... -
Development of novel organocatalysts towards the kinetic and dynamic resolution of chiral enolisable anhydrides
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2018)In this thesis we explore the possibilities offered by the bifunctional properties of a series of organocatalysts derived from cinchona alkaloids for the promotion of novel asymmetric transformations. In particular, we ... -
Development of novel porous materials via polymer self-assembly and phase separation
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2023)Polymer self-assembly is an ever-growing field that is attracting interest from a diverse range of research topics, which include the production of functional devices and membranes for electronic, optical and energy ... -
Development of Novel Thiol-ene Ligation Strategies for Thiosugar and Peptide Synthesis
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2019)This thesis, entitled ?Novel Thiol-ene Ligation Strategies for Thiosugar and Peptide Synthesis?, is composed of 6 Chapters. The first chapter gives an overview of the radical-mediated thiol-ene and thiol-yne addition ... -
The development of radical methodologies for the syntehsis of thiolactones and carbon-sulfer bond formation
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)This thesis entitled "The Development of Radical Methodologies for the Synthesis of Thiolactones and Carbon-Sulfur Bond Formation" is divided into 7 chapters in which Chapter 1, the introduction, presents an overview of ... -
Development of Stimuli-responsive Materials for Direct Laser Writing for the Realisation of Microactuators
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2024)Two-photon polymerisation (2PP) is a laser-based fabrication technology which can be used to fabricate complex 3D microstructures with feature sizes ~100 nm. This thesis assesses the state of the art in 2PP and presents ... -
Development of Supramolecular Coordination Materials Using Naphthalimide and 2,6-bis(triazol-4-yl)pyridine Motifs
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2022)Structural coordination chemistry can be ultilised to develop functional supramolecular materials such as coordination polymers, soft materials, and metal organic frameworks. By applying the principles of self-assembly an ... -
Development of Synthetic Peptides as Functional Probes for the Lipoprotein Biosynthesis Pathway in Bacteria
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)Protein lipidation is a critical post-translational modification that occurs in all bacteria. The essential enzymes involved in this modification are exclusive to bacteria and have demonstrated potential as antibiotic ... -
Development of synthetic strategies towards multiporphyrin arrays
(Trinity College (Dublin, Ireland). School of Chemistry, 2011)The aim of this research was to develop synthetic strategies for the construction of multiporphyrin arrays with enhanced π-conjugation. Porphyrin oligomers with extended conjugation display a bathochromic shift in their ... -
Development of Unconventional Amide Bond Forming Methodologies
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2020)A novel methodology for the protection of amines and diamines using 2,2-pyridil, under the influence of N-heterocyclic carbene (NHC) catalysis, has been developed. Extensive experimentation which included the design and ... -
Diffusion within fluorite structured materials and the effect of defects
(Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2018)There is a current global movement toward renewable sources and away from non- renewable energy sources. This can be attributed to the limited resources and harmful effects, both economic and environmental, of non-renewables. ... -
Diquaternerised and Ru(11) based polypyridyl conjugates as biological probes and phototherapeutic agents
(Trinity College (Dublin, Ireland). School of Chemistry, 2011)This Thesis entitled 'Diquaternerised and Ru(ll) Based Polypyridyl Conjugates as Biological Probes and Phototherapeutic Agents' is divided into 8 Chapters. Chapter 1, the introduction, gives a brief introduction to the ...