dc.contributor.author | MURPHY, DEIRDRE | en |
dc.contributor.author | BARRY, JOSEPH | en |
dc.date.accessioned | 2014-07-22T10:16:12Z | |
dc.date.available | 2014-07-22T10:16:12Z | |
dc.date.issued | 2013 | en |
dc.date.submitted | 2013 | en |
dc.identifier.citation | Murphy DJ, Mullally A, Cleary BJ, Fahey T, Barry J, Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes--a prospective cohort study., BMC pregnancy and childbirth, 13, 2013, 8 | en |
dc.identifier.other | Y | en |
dc.identifier.uri | http://hdl.handle.net/2262/70456 | |
dc.description | PUBLISHED | en |
dc.description.abstract | Background
There has been limited research addressing whether behavioural change in relation to alcohol exposure in pregnancy results in better perinatal outcomes.
Methods
A cohort study of 6725 women who booked for antenatal care and delivered in a large urban teaching hospital in 2010–2011. A detailed history of alcohol consumption pre-pregnancy and during early pregnancy was recorded at the first antenatal visit with follow-up of the mother and infant until discharge following birth. Adverse perinatal outcomes were compared for ‘non-drinkers’, ‘ex-drinkers’ and ‘current drinkers’.
Results
Of the 6017 (90%) women who reported alcohol consumption prior to pregnancy 3325 (55%) engaged in binge drinking and 266 (4.4%) consumed more than 14 units on average per week. At the time of booking 5649 (94%) women were ex-drinkers and of the 368 women who continued to drink 338 (92%) had a low intake (0–5 units per week), 30 (8%) an excess intake (6-20+ units per week) and 93 (25%) reported at least one episode of binge drinking. Factors associated with continuing to drink in early pregnancy included older maternal age (30–39 years), (OR 1.6; 95% CI 1.3 to 1.8), Irish nationality (OR 3.1; 95% CI 2.2 to 4.3) and smoking (OR 2.6; 95% CI 1.9 to 3.5). Ex-drinkers had similar perinatal outcomes to non-drinkers. Compared to non-drinkers current drinking was associated with an increased risk of intrauterine growth restriction (IUGR) (13% versus 19%, crude OR 1.6; 95% CI 1.1 to 2.2, adjusted OR 1.2; 95% CI 0.8 to 1.8). The greatest risk of IUGR was among women who continued to both drink and smoke, (9% versus 32%, crude OR 4.8; 95% CI 3.3 to 7.0, adjusted OR 4.5; 95% CI 3.1 to 6.7).
Conclusions
Public Health campaigns need to emphasise the potential health gains of abstaining from both alcohol and smoking in pregnancy. | en |
dc.format.extent | 8 | en |
dc.language.iso | en | en |
dc.relation.ispartofseries | BMC pregnancy and childbirth | en |
dc.relation.ispartofseries | 13 | en |
dc.rights | Y | en |
dc.subject | Perinatal outcomes | en |
dc.subject | Pregnancy | en |
dc.subject | Prospective cohort study; | en |
dc.subject | Alcohol exposure | en |
dc.title | Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes--a prospective cohort study. | en |
dc.type | Journal Article | en |
dc.type.supercollection | scholarly_publications | en |
dc.type.supercollection | refereed_publications | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/murphyd4 | en |
dc.identifier.peoplefinderurl | http://people.tcd.ie/joebarry | en |
dc.identifier.rssinternalid | 84144 | en |
dc.identifier.doi | http://dx.doi.org/10.1186/1471-2393-13-8 | en |
dc.rights.ecaccessrights | openAccess | |